RNA Details
Disease Name
keloid
Tissue
skin
RNA Symbol
miR-1224-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
immunofluorescence; flow cytometry etc.
Target
NA
Pathway
NA
PubMed ID
Title
"Tumor suppressive role of miR-1224-5p in keloid proliferation, apoptosis and invasion via the TGF-beta1/Smad3 signaling pathway"
Year
2018
Function
"Overexpression of mir-1224-5p led to inhibition of keloid fibroblast proliferation, promotion of apoptosis and decrease of migration and invasion. Our results suggest that downregulation of mir-1224-5p may be one of the mechanisms involved in the occurrence and development of keloids."